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Men who are unable to obtain an erection during sexual activity are said to have impotence or erectile dysfunction. The best drug for male sexual dysfunction is Tadarise 20 Mg. Tadalafil, an ingredient in the aforementioned medication, helps men's penile tissue relax. The effects of this medication take 36 hours to manifest. Take this medication as directed; however, do not break or chew the pill. Follow your doctor's instructions when taking this medication. Take this medication without regard to cold drinks or heavy meals.