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Products sold as dietary supplements come with a Supplement Facts label that lists the active ingredients, the amount per serving (dose), and other ingredients, such as fillers, binders, and flavorings. The manufacturer suggests the serving size, but your health care provider might decide a different amount is more appropriate for you.

Effectiveness
Some dietary supplements can help you get adequate amounts of essential nutrients if you don’t eat a nutritious variety of foods. However, supplements can’t take the place of the variety of foods that are important to a healthy eating routine. To learn more about what makes a healthy eating routine, the Dietary Guidelines for Americansexternal link disclaimer and MyPlateexternal link disclaimer are good sources of information.

Some dietary supplements can improve overall health and help manage some health conditions. For example:

Calcium and vitamin D help keep bones strong and reduce bone loss.
Folic acid decreases the risk of certain birth defects.
Omega-3 fatty acids from fish oils might help some people with heart disease.
A combination of vitamins C and E, zinc, copper, lutein, and zeaxanthin (known as an Age-Related Eye Disease Study [AREDS] formula) may slow down further vision loss in people with age-related macular degeneration (AMD).
Many other supplements need more study to determine if they have value. The U.S. Food and Drug Administration (FDA) does not determine whether dietary supplements are effective before they are marketed.

Safety and Risk
Many supplements contain active ingredients that can have strong effects on the body. Always be alert to the possibility of a bad reaction, especially when taking a new product.

You are most likely to have side effects from dietary supplements if you take them at high doses, or instead of prescribed medicines, or if you take many different supplements. Some supplements can increase the risk of bleeding or, if taken before surgery, can change your response to anesthesia. Supplements can also interact with some medicines in ways that might cause problems. Here are a few examples:

Vitamin K can reduce the ability of the blood thinner warfarin to prevent blood from clotting.
St. John’s wort can speed the breakdown of many medicines and reduce their effectiveness (including some antidepressants, birth control pills, heart medications, anti-HIV medications, and transplant drugs).
Antioxidant supplements, such as vitamins C and E, might reduce the effectiveness of some types of cancer chemotherapy.
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